Thrombosis is a harmful activation of the clotting process, which is associated with the occurrence of blood vessel-related diseases. Pathological enhancement of the clotting cascade causes thrombosis ...

The tide of the blood coagulation cascade turns by a switch in thrombin specificity. Two new structures reveal how thrombomodulin's EGF domains flip the switch by blocking old substrates and docking ...

Under homeostatic conditions, the body is maintained in a finely tuned balance of coagulation and fibrinolysis. See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation ...

Nov. 29, 2004 — Although there is a statistically significant difference in coagulation testing done from plastic vs glass collection tubes, this difference is not clinically significant, according to ...

The companies’ “Change the Target. Change What’s Possible” targets the potential of Factor XIa inhibition in the development ...

Blood coagulation is a balancing act. Too much clotting can lead to strokes. But not enough clotting can lead to uncontrolled bleeding. That balance is particularly important for patients with ...

image: (top) Citrated whole blood is put between electrodes. When the blood starts coagulation, the permittivity measured by alternating current (AC) increases in relation to the aggregation and ...